Nutrigenomics and personalized diets


Nutritional interventions tailored individually to each patient are fundamental in the treatment of chronic diseases and health strategies.


A person's gene-nutrient interactions, as well as variations in the composition of the gut microbiome, are key components in planning dietary interventions.


Despite recent advances in our understanding of nutrigenomics and the role of the gut microbiome in energy extraction, the idea that a given food will have the same effect on all individuals is still widespread.


However, studies continue to show that, after ingesting identical foods, metabolic responses such as blood triglycerides, glucose, and insulin responses, for example, vary considerably between individuals.


Nutrigenomics, the science that explores how individual genetic differences play a role in how an individual responds to diet, may account for the variability in glucose responses and the overall impact of diet.


Metabolomics, on the other hand, identifies how small molecules and metabolites found in the body can vary across diets, and can be used to determine potential biomarkers of disease risk and track the effects of specific foods.


An important clinical conclusion from this recent nutritional research is that each patient is unique and may not respond in the same way to a given dietary plan at different times or in the same way as other patients.


There are a variety of tests available: Nutritional Genomics, Urine Metabolomics, Gut Microbiota Mapping, etc.


In an era where personalized data is more readily available than ever before, healthcare professionals can achieve remarkable results in assessing and treating patients according to their individual needs.


Sources:


https://www.nature.com/articles/s41591-020-0934-0


https://link.springer.com/article/10.1007/s13300-021-01174-z


https://link.springer.com/article/10.1007/s11356-022-24045-x


https://www.sciencedirect.com/science/article/abs/pii/S1568163722000915?via=ihub


https://www.jpmh.org/index.php/jpmh/article/view/2754


https://www.sciencedirect.com/science/article/abs/pii/S0272271222000750?via=ihub